Rapamycin increases oxidative stress response gene expression in adult stem cells
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چکیده
منابع مشابه
Rapamycin increases oxidative stress response gene expression in adult stem cells
Balancing quiescence with proliferation is of paramount importance for adult stem cells in order to avoid hyperproliferation and cell depletion. In some models, stem cell exhaustion may be reversed with the drug rapamycin, which was shown can suppress cellular senescencein vitro and extend lifespan in animals. We hypothesized that rapamycin increases the expression of oxidative stress response ...
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Stem Cell Group, Nordic EMBL Partnership, Centre for Molecular Medicine Norway (NCMM), University of Oslo, Oslo, Norway City University of Hong Kong, Kowloon, Hong Kong Center for Mitochondrial Medicine and Free Radical Research, Changhua Christian Hospital, Changhua City, Taiwan Biotechnology Centre, Silesian University of Technology, Gliwice, Poland Mackay Medical College, New Taipei City, Ta...
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ژورنال
عنوان ژورنال: Aging
سال: 2012
ISSN: 1945-4589
DOI: 10.18632/aging.100451